SAFETY OF HEALTH PROVIDERS IN THE PHYSICAL HANDLING OF PATIENTS IN NURSING CARE


The DNMT3A PWWP domain is essential for the normal DNA methylation landscape in mouse somatic cells and oocytes.

DNA methylation at CG sites is important for gene regulation and embryonic development.In mouse oocytes, de novo CG methylation requires preceding transcription-coupled histone mark H3K36me3 and is mediated by a DNA methyltransferase DNMT3A.DNMT3A has a PWWP domain, which recognizes H3K36me2/3, and heterozygous mutations in this domain, including D

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Examining heterogeneity of stromal cells in tumor microenvironment based on pan-cancer single-cell RNA sequencing data

Tumor tissues contain both tumor and non-tumor cells, which include infiltrated immune cells and stromal cells, collectively called the tumor microenvironment (TME).Single-cell RNA Storage Box sequencing (scRNAseq) enables the examination of heterogeneity of tumor cells and TME.In this review, we examined scRNAseq datasets for multiple cancer types

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